Participants reported that particular requirements and structural elements of TREC I were important facilitators of TD team science. Participants said they were motivated to persevere in their goal of TD integration despite challenges related to defining TD research, understanding how to engage in TD team science, and comprehending its potential value, in part because of NCI's explicit expectations for TD integration. This was reflected in the funding announcement and NCI leadership's sustained emphasis on TD integration in communications with grantees over the course of the initiative.
