Pathway and functional genomic analyses were performed using the GWAS results for each of the MDD meta-analyses. These included DEPICT analyses44, reference to RegulomeDB45 (http://www.regulomedb.org/) and to the Genotype-Tissue Expression Portal (http://www.gtexportal.org) for independent SNPs with P < 1.0 × 10−5 and all genome-wide significant SNPs (P < 5.0 × 10−8, nSNPs = 6). Further information on pathway and functional genomic analysis can be found in the Supplementary Methods.
