In conclusion, this study provides new information with the use of DTI to elucidate changes in white matter microstructure associated with adolescent MJ+ALC use. Findings reveal prominent aberrancies in fronto-parietal networks and fiber projections within circuits responsible for modulating complex cognitive, motor, and sensory processing. Findings implicate possible neuroadaptive anatomic changes that can be applied to future studies of connectivity to determine how alterations in specific tracts might influence efficient cognitive processing.
