Sex-specific quantile–quantile and Manhattan plots are shown in Figure 3. Three loci were genome-wide significant in the male-only GWAS (n = 14,154 cases, n = 17,948 controls). No SNPs surpassed the genome-wide significance threshold in the female-only GWAS (n = 4945 cases, n = 16,246 controls). (See Supplemental Table S8 for top 10 LD-independent SNPs for each GWAS, annotated with the nearest gene.)