In spite of the conceptual limitations, “localizing” models are still the main approach to the identification of pathological changes as a component of the networks’ structural and functional abnormalities [81]. We hypothesize that dysregulation of neurogenesis, neuronal migration and maturation is also reflected in qualitative, focal, developmental alterations of brain microarchitecture. The aim of this study is to detect the pattern of focal, qualitative, developmental defects in autism brain, including their type, topography and severity, and to identify the structures and brain regions that are prone to developmental alterations in autism.
