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Chunk #26 — Discussion

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Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: possible differential markers of affective and impulsive pathways of risk for alcohol use disorder.
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positive emotion, even when excessive and problematic, is less likely to increase as a function of recent life stress, whereas convergent data from animal models49, 50 and humans51, 52 suggests that stress can increase behavioral disinhibition and impulsive responding. Thus, perhaps the high VS-low amygdala phenotype we identify more directly shapes the risk pathway characterized by high impulsivity and behavioral disinhibition, rather than the risk pathway associated with the enhancement of positive emotion.