in this cohort: as shown in Table 4: 23.0% of men and 11.3% of women reported using cannabis at least 100 times, 14.5% of men and 7.1% of women reported using it daily during their period of heaviest use, 23.3% of men and 10.6% of women met DSM criteria for cannabis abuse, and 14.8% (males) and 6.8% (females) met lifetime criteria for cannabis dependence. Across all these measures there were significant sex differences with some suggestion that the magnitude of these differences increased with increasing severity of cannabis involvement: for example, males were 1.66 (95% CI = 1.43–1.92) times more likely to report lifetime use but 2.44 (95% CI = 1.05–3.90) times more likely to meet criteria for cannabis abuse or dependence.