Chunk #23 — RESULTS — Effects of risk genotypes on hippocampal volume and neurochemistry

Source

The neuronal transporter gene SLC6A15 confers risk to major depression.

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yes

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The imaging data thus suggest that risk allele-carrier status is associated with a decrease in hippocampal neuronal integrity already in healthy controls, and that patients with recurrent major depression and the risk genotype experience an exacerbated reduction in hippocampal volume.