Chunk #22 — Adenosine, Receptors and Functions in the CNS — Adenosine A2AR and Functions in the CNS

Source

Purinergic Receptors of the Central Nervous System: Biology, PET Ligands, and Their Applications.

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Application of pharmacological tools of the A2A receptors have shown a significant benefit in treating several CNS disorders,119 and thus, PET imaging of the A2A receptors has been useful to study in vivo expression of A2A receptors in normal and under pathophysiological brains.