Chunk #13 — 2. Results and Discussion — 2.2. Glx (Complex of Glutamate, Glutamine and GABA)

Source

Adding Sarcosine to Antipsychotic Treatment in Patients with Stable Schizophrenia Changes the Concentrations of Neuronal and Glial Metabolites in the Left Dorsolateral Prefrontal Cortex.

Embedded

yes

Text

An evaluation of Glx level was performed instead of separate glutamine, glutamate and GABA evaluations, as their peaks closely overlap in 1.5 Tesla spectroscopy. Glx is a surrogate of glutamatergic transmission in grey matter as the concentration of glutamate is five times higher than that of glutamine, and 10 times higher than GABA [46].