paperKB
coga / coga-kb
Help
Sign in

Chunk #7 — Method — Axis I Disorders

Source
The structure of genetic and environmental risk factors for syndromal and subsyndromal common DSM-IV axis I and all axis II disorders.
Embedded
yes

Text

Twelve axis I disorders were included in these analyses: major depression, dysthymia, panic disorder, agoraphobia, specific phobia, social phobia, generalized anxiety disorder, eating disorders, somatoform disorder, alcohol abuse or dependence, illicit drug abuse or dependence, and conduct disorder. Except for conduct disorder, initial analyses of these disorders were performed using DSM-IV diagnoses automatically generated by the M-CIDI data program. However, stable solutions were unobtainable because of small or zero cell frequencies for a number of these diagnoses. We therefore created three ordered categories (unaffected, subsyndromal, and fully syndromal) for 10 of these disorders, which substantially improved the stability of our estimates. Our definitions for the subsyndromal categories are detailed briefly in Table 1 and in more detail in Table S1 in the data supplement that accompanies the online edition of this article.