When minorities are included in biomedical research, they may be inappropriately aggregated into large groups, such as “Asian” or “Latino.” This is partly related to the problem of subgroup size—aggregation is necessary to get enough people in each subgroup to produce statistically significant results. But it comes at the cost of true subgroup homogeneity, and it masks the fact that severe health disparities often exist among racial and ethnic subgroups within the minority population.16