of the DRD4 VNTR had significantly greater neural response to alcohol taste cues (i.e., cue-exposure) in the orbitofrontal, cortex, anterior cingulate gyrus, and striatum prior to a priming dose of alcohol (i.e., cue-exposure), but not after a priming dose. These findings suggested that the effects of this polymorphism may be in response to alcohol cues and not necessarily the neuropharmacological effects of alcohol ingestion. While the present study cannot disentangle the effects of presence of alcohol cues from its pharmacology, it is consistent with the Filbey et al. (2008) results.
