Differential expression of neuronal marker ADCY1 in the AHBA corrected for cell-type abundance.ADCY1 is a neuronal marker identified as one of the 960 Braak stage-related genes (BRGs). We found it was still significantly differentially expressed between samples from region R1 (black) and R6 (red) when correcting for one of the five main cell-types with PSEA (BH-corrected P < 0.05, t-test). Significant BH-corrected P-values are highlighted in red text together with cell-type specific fold-changes (FC; slope change of red line).
