Using 1000Genomes data (as described in the Methods) and commonly used but different methodological choices in the construction of polygenic scores, we demonstrate that no simple conclusions can be drawn about polygenic scores and height for worldwide populations. In Fig. 4 we plot average polygenic scores for height of 1000Genomes populations on the x-axis, using three sources of weights for constructing scores (PRS = polygenic risk score):4a (top row) GIANT Consortium18 based scores: PRSheight_GIANT4b (middle row) UKBiobank44 based scores from the NealeLab: PRSheight_UKBiobank4c (bottom row) East Asian GWAS based scores45 from He et al: PRSheight_EastAsian
