Chunk #17 — Identifying Specific Genes Related to AOD Dependence — Genes Encoding Proteins Involved in Neurotransmission — Genes Encoding the GABAA Receptor
The GABAA receptor is composed of five subunits that are encoded by numerous genes, most of which are located in clusters. Thus, chromosome 4 contains a cluster comprising the genes GABRA2, GABRA4, GABRB1, and GABRG1; chromosome 5 contains GABRA1, GABRA6, GABRB2, and GABRG2; and chromosome 15 contains GABRA5, GABRB3, and GABRG3 (see http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene).
