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Chunk #27 — Discussion

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Genome-wide association study of stimulant dependence.
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We found an association of stimulant dependence with novel risk genes and genes that were previously identified as risk factors for other addiction traits. Post-GWAS eQTL and pathway analyses provide insight into the biological mechanisms that contribute to amphetamine dependence. In addition, our results suggest the presence of a shared genetic basis for stimulant dependence and other psychiatric traits.