Chunk #33 — Materials and methods — Genetic evidence — Defining genetic evidence

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Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval.

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yes

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However, trait similarity is a real number in [0, 1], so we can define another genetic evidence function EC from G×T to [0, 1] EC(g,t)=max{S((g,t),(ga,ta)):(ga,ta)∈A}