Two-way interactions for any significant main effects were tested for each class of disorder. After adjusting for family-wise experimental errors with a Bonferroni correction, no interactions were observed between individual and parental demographic correlates and anxiety or behavior disorders. There were four significant interactions for other disorders: (1) the prevalence of mood disorders was higher in White adolescents in homes with higher levels of parental education than that in Blacks and Hispanics; (2) rates of substance use disorders increased more dramatically with age for males than females; (3) sex differences in substance use disorders were largest for Blacks compared to other ethnic groups; and (4) increased rates of substance use disorders were observed among Hispanic adolescents whose parents were divorced, however, rates were decreased among Blacks whose parents were never married or divorced.