Our analysis shows the large burden of disease attributable to primary and secondary tobacco smoking and to particulate matter pollution in household and ambient environments. The magnitude of disease burden from particulate matter is substantially higher than estimated in previous comparative risk assessment analyses. For example, ambient particulate matter pollution was estimated in the previous comparative risk assessment7 to account for 0·4% of DALYs in 2000 compared with 3·1% in GBD 2010 based on interpolating our 1990 and 2005 results; for household air pollution from solid fuels the comparison is 2·7% in the previous comparative risk assessment versus 5·3% based on GBD 2010.
