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Chunk #20 — Results — Neurocognitive Correlates of White Matter Anomalies — Fractional anisotropy

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Neurocognitive correlates of white matter quality in adolescent substance users.
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For users (n=36), FA in the right ILF, a cluster where FA was lower than that of controls, was positively correlated with Digit Span total scaled score (r = .38, p = .02) and Digit Symbol total scaled score (r = .35, p = .03) (see Table 2). Conversely, clusters in which users' FA exceeded that of controls showed bidirectional associations. CVLT-II List A Trial 1 (r = .47, p = .004) and D-KEFS TMT Switching (r = .55, p = .001) were positively associated with FA in the occipital-cuneus region, whereas Digit Span total (r = -.33, p = .04) showed a negative relationship with FA in the anterior limb of the internal capsule.