genetic model with MAF = 0.1 (0.3), the CPD sample (N = 915) had 54% (89%) power to detect a main effect of 0.1. For the two binary traits in EAs, under a log-additive genetic model with MAF = 0.1 (0.3), our study had 66% (94%) and 63% (93%) power to detect an effect with a relative risk of 1.5 for ND (716 cases/223 controls) and FTND (705 cases/208 controls), respectively.