ChromatinAssay allows for the storage and retrieval of information needed for the analysis of single-cell chromatin data, including genomic ranges associated with each feature in the experiment, gene annotations, genome build information, DNA motif information and on-disk storage of single-cell data as tabix-indexed fragment files44. Crucially, the specialized ChromatinAssay can be stored in a Seurat object side by side with standard Seurat Assay-class objects to facilitate analysis of multimodal single-cell data (Fig. 1c).
