A continuing driver for developments in Ensembl is its active involvement in many data generation and analysis projects. Recent examples have been the Rat haplotype project (6–8) and the ENCODE project (9). Dealing with data generated by the ENCODE project in particular had led to the development of specific algorithms for experimental data handling, such as approaches for designing and assessing whole genome tiling arrays (10). Ensembl has continued to be strongly involved in analysis for publications of new vertebrate genome sequences, particularly through its genesets (11–13) (see below).
