service agencies that want to apply the newest knowledge about genetic risks for disorders but do have access to their clients' DNA profile (for technological and ethical reasons) can leverage knowledge from studies that use a behavioral-molecular genetic approach to target phenotypic behaviors. Data from the EGDS will be used to evaluate associations between polymorphisms and genetically influenced behaviors (and the moderating or mediating effect of the environment on such behaviors) and could be directly applied to the translation from DNA to a risk behavior. Although such translational approaches are still years from being implemented and will involve significant ethical discussion, studies such as the EGDS and others described in this special issue will be in place as a resource as the field develops.