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Chunk #0 — 1. Introduction

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Review: Pharmacogenetics of alcoholism treatment: Implications of ethnic diversity.
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There have been an abundance of both animal and human studies highlighting the importance of genetic factors in alcohol use disorder (AUD) and how these factors, in turn, affect response to treatment (for review see1). Genetic factors are thought to account for nearly half of the vulnerabilities leading to AUD as determined using twin, adoption, and family studies.2 Furthermore, ancestry significantly influences alcohol response and patterns of alcohol use.2