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Chunk #9 — SUMMARY STATISTICS IN THE GWAS CATALOG

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The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019.
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will deliver a deposition tool to simplify the process of deposition and link it to curation activities, with the aim of integrating these processes to provide access to richer data as quickly as possible. As of September 2018, 284 SS datasets from 116 publications, representing over 6 × 109 individual variant-trait statistics are available from the Catalog. We encourage authors of all studies in the Catalog to submit their SS and have campaigned for deposition via Twitter (@GWASCatalog). Sharing of SS is also promoted at conferences and we engage with consortia carrying out large-scale genotyping/phenotyping projects. For example, we have worked with representatives from the MAGIC Consortium (www.magicinvestigators.org) and Immunobase (https://www.immunobase.org/) to make available SS from their GWAS studies (26,27). We observe a positive trend within the genetics community in sharing SS; over the last 12 months the proportion of studies with SS in the GWAS Catalog has increased from 1.4% to 5% (Figure 2).