In summary, the general theme of the contributions from the Admixture Group was inferring, accounting for, and incorporating ancestry admixture. Despite the diversity of methods and applications considered, a common finding was that genetic analyses in admixed populations substantially benefit from appropriate proxies for the ancestral populations. This applies to both local and global ancestry estimation, admixture mapping, and genotype imputation. The sparsity of adequate reference population samples - for example, specific reference panels for Native American subpopulations – however, is currently a limitation in genetic analyses of populations with admixed ancestry. As public resources of genotype and sequence data from diverse ancestral populations expands in parallel with continued development of powerful and computationally efficient statistical methods, the future of genetic studies in admixed populations is promising.
