repeats, structural variants, and rare SNPs that are more likely to be seen with NGS. So far, molecular genetic studies have linked variation across chromosomes 1, 2, 3, 4, 7, and 8 to diagnoses of AD (Foroud et al., 2000; Nurnberger et al., 2001; Reich et al., 1998; Wang et al., 2004; Williams et al., 1999), as well as chromosomes 5, 6, 9, 15, 16, and 21 using quantitative phenotypes of AD (e.g., maximum number of drinks) and neurophysiological phenotypes (e.g., event related potentials, such as P300) that are often comorbid with AD and other psychiatric disorders (Almasy et al., 2001; Begleiter et al., 1998; Foroud et al., 1998; Ghosh et al., 2003; Hill et al., 2004; Jones et al., 2004; Kuo et al., 2006; Porjesz et al., 2002; Saccone et al., 2000; Schuckit et al., 2001).
