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Chunk #21 — RESULTS

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Comparison of alcoholism subtypes as moderators of the response to sertraline treatment.
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Table 1 shows the baseline characteristics for the 134 patients subtyped using each of the three approaches. Each method yielded subgroups that differed significantly from one another on age, income, SIP total score, and the prevalence of lifetime cannabis dependence and ASPD. Type B individuals and EOAs (based on either age-of-onset approach) were younger and had higher SIP scores and a higher lifetime prevalence of cannabis dependence and ASPD than Type A individuals and LOAs, respectively. Type B alcoholics also had a higher lifetime prevalence of both cocaine dependence and conduct disorder than Type A alcoholics. None of the subtyping approaches yielded groups that differed from one another on the prevalence of a lifetime diagnosis of major depressive disorder, which could be relevant given that the study evaluated the effects of sertraline, an antidepressant medication.