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Chunk #25 — MEA technology — Advances in MEA and probe devices

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Revealing neuronal function through microelectrode array recordings.
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cells within the array, allows the use of complex routing paths to rewire a subset of electrodes to the available readout and stimulation channels in a flexible manner. Often, such an approach is sufficient to observe biological phenomena of interest, as typically not all electrodes exhibit activity. However, experimental protocols tend to get more complex, as one needs to select the “right” electrodes during the experiment. One of the protocols commonly used for such devices is to first scan the entire array in static mode, i.e., record from each rectangular sub block for, e.g., a few minutes, run some online or quasi online data processing on the recorded data, and select a more refined subset based on the recorded activity and the scientific objective of the experiment.