The breadth of the diagnostic survey allowed us to identify multiple, clinically meaningful latent classes of psychiatric disorder in the offspring. Our study is unusual in its simultaneous modeling of familial and measured environmental risk factors. The twin fathers, in particular, are well-characterized by their own reports of psychopathology, obviating the need to rely on maternal report of paternal psychopathology, with their known limitations (Waldron et al 2012). Additional strengths include the large sample size and the non-clinical nature of the samples that enhance generalizability and permit modeling a wide array of environmental factors, while avoiding bias inherent to treatment l samples. The structured, systematic method of data collection reduces interviewer bias.
