There is also substantial evidence for generalization of these results from addiction. This evidence comes from the significant overlaps between the molecular genetics of addiction and the molecular genetics of a number of related phenotypes and disorders. Overlap with bipolar disorder provides one of several likely psychiatric diagnoses for which shared genetic influences are likely a priori, based on the substantial heritabilities of both addiction and the high frequency of addiction/bipolar disorder comorbidity [146, 147]. This same logic suggests that abundant shared genetics may well also underpin the frequent comorbidities between addictions and antisocial personality/conduct disorders [251]. Less compelling evidence points to overlaps with other depressive, anxiety and schizophrenic disorders as well [251].
