trimethylation (H3K4me3) data to identify expression differences in post-mortem hippocampus tissue collected from alcohol and cocaine dependent cases and matching controls (Zhou et al., 2011). Similarly, Schumann et al. (2011) followed up on their GWAS findings that pointed to AUTS2 as a regulator of alcohol consumption, by demonstrating significant expression-level differences in human prefrontal cortex, and whole-brain extracts from mice, as well as, reduced consumption in drosophila insertion mutants.
