In contrast, LFP oscillations in ventral striatum have been less studied. Ventral striatum, and the nucleus accumbens in particular, is a central site in the processing of reward information, and has a complex role in a wide range of goal-directed, motivated behaviors (Berridge, 2007; Cardinal et al., 2002; Day and Carelli, 2007; Ikemoto and Panksepp, 1999; Kelley, 2004; Nicola, 2007). Anatomically, it is well placed to integrate inputs from frontal cortex, amygdala, and hippocampus with dopaminergic input from the ventral tegmental area to influence motor actions (Goto and Grace, 2008; Mogenson et al., 1980; Voorn et al., 2004). Accordingly, ventral striatum is a key site for mechanisms involved in addiction (Hyman et al., 2006; Kalivas and Volkow, 2005; Wise, 2008), and is increasingly studied in the context of other reward- and motivation-related pathologies such as depression (Nestler et al., 2002; Salamone et al., 2005; Vassoler et al., 2008; Yadid and Friedman, 2008) and obsessive-compulsive disorder (OCD; Münte et al., 2008; Sturm et al., 2003; Wise and Rapoport, 1989). Ventral striatum is starting to be explored as a DBS target to
