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Chunk #17 — Results — Characterization of Molecular Mechanisms Underlying Variable Erythroid Differentiation Potential

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Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential.
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more, and annotated to the TSS of the nearest protein coding gene. We found several genes that are likely involved in the differentiation of the lines to contain DMCs (Table S8). For example, we found that CpGs associated with NUCB2 and RB1 were more highly methylated in cells derived from donor T55 than T42. Reciprocally, CpGs associated with the genes CPSF6, IBTK, and PFDN4 were more highly methylated in T42 than in T55.