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Chunk #39 — Results — 5. Haplotype effects on Subjective Responses to Alcohol — 5. B. Block 2: GABRA2 region — 5. A.1. Visual Analog Drug Effect Questionnaire (VAS)

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GABRA2 markers moderate the subjective effects of alcohol.
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Carriers of one or two copies of block 2, haplotype 1, GT, had significantly higher mean alcohol “Positive” effects scores (i.e., the sum of “Good, Like and Best” effect scores) of 41.54 (SE = 3.47) than non-carriers, who had mean alcohol “Positive” effects score of −4.46 (SE = 8.50), after adjusting for time and BAC (F(1, 50) = 6.53, p=0.0137) (Table 5).