in the course of development (Yordanova and Kolev, 1998, 2009). Therefore, given these suggested findings in the current study, it is possible that the minor alleles of KCNJ6 could be associated with lack of frontalization and/or delayed brain maturation. It is also important to mention that the genotype × condition interaction was not significant, indicating that the main effect of genotype may be non-specific and pertain to the feedback evaluation process in general, rather than to loss or gain specifically. Since theta-band responses can be elicited by a variety of task-relevant stimuli, the effect observed could be non-specific. On the other hand, significant condition × region effect suggested outcome-specific theta activity, in which gain manifested posteriorly focused (parietal) theta power while the loss condition showed relatively anterior (fronto-central) focus. With regard to visual oddball paradigm, Kang et al. (2012) reported that theta power related to target processing was frontally focused, and the genome wide association was strongest for the frontal region, followed by central and parietal regions. Further studies are needed to ascertain the effects of task-specific theta activity on the genotypes of KCNJ6 polymorphisms. Additional studies are also required to elucidate the exact role of variations in KCNJ6 in
