Chunk #31 — Statistical analysis — Family-based studies

Source

Genome-wide association studies and the genetic dissection of complex traits.

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yes

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analysis in unrelated subjects to confirm associations of SNPs in BCL11A with fetal hemoglobin expression in β-thalassemia carriers and sickle cell anemia patients. In general, positive associations from both linkage and association studies strengthen the evidence for true positive findings [85].