While the method uses Approximate Bayes Factor computations (ABF, [20], and Methods), no iterative computation scheme (such as Markov Chain Monte Carlo) is required. Therefore, computations are quick and do not require any specific computing infrastructure. Precisely, the computation time behaves as , where Q is the number of variants in the genomic region and d the number distinct associations (typically d = 2, assuming two traits and at most one causal variant per trait).
