were interviewed on three occasions: first by the investigator during the initial consent meeting, then by the Master’s level clinical interviewer, and finally by the physician during the physical examination. Few women met criteria for any lifetime Axis I disorders; 3 women in each group met past criteria for major depression and 3 women in the FHP group met past criteria for alcohol abuse. Women who abstained from alcohol or typically drank more than 20 drinks per week in the past year were also excluded. Our original intention was to recruit FHN and FHP women who were all light drinkers, similar to our previous studies comparing FHP and FHN women (Evans et al., 2000; Evans and Levin, 2003). However, in the ensuing years, we have seen a dramatic increase in alcohol consumption in women overall (see Keyes et al., 2008) and particularly FHP women. Therefore, in this study FHP women could be moderate drinkers as long as they did not meet criteria for alcohol abuse or dependence and drank less than 20 drinks/week. However, we maintained our previous criteria of requiring FHN women to be light drinkers because we have previously shown differences in the response to alcohol between light