The large iPSYCH2012 sample will provide a solid foundation for a range of studies in decades ahead. We have completed genotyping and plans are advanced for a range of other analyses, including an update and major expansion with cases diagnosed since 2012, as well as including new diagnostic case groups. The sample is thus not only a rich database for research in the current version - it also constitutes a logistic and organizational framework for future studies, although each new study will require relevant ethical permissions. Most other genetic studies are based on samples of convenience rather than utilizing true population-based samples. To our knowledge, no large-scale population-based sample with genome-wide association study data exists elsewhere. In particular, we are confident that the iPSYCH2012 sample provides an important resource to explore novel ways to combine genetic, phenotypic and environmental factors. Phenotypic and environmental factors are readily available through record linkage between the numerous Danish registers or assayed from neonatal dried blood spots.
