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Chunk #6 — Maternal car in the rat programs behavioral and HPA responses to stress

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Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome.
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frequency of LG do not occur simply as a function of time in contact with pups. High- and low-LG mothers raise a comparable number of pups to weaning, and there are no differences in the weaning weights of the pups, suggesting an adequate level of maternal care across the groups. These findings also suggest that we are examining the consequences of variations in maternal care that occur within a normal range. Indeed, the frequency of both pup LG is normally distributed across large populations of lactating female rats.65