Mood induction did not, in and of itself, significantly alter medial prefrontal responses to the alcohol cues, although some trends in the data suggest that negative mood might have enhanced the contrast between the AcO and AppCo stimuli in the left vmPFC. Interestingly, mood did alter subjective reports of craving for alcohol and grape juice, in that the contrast between alcohol and grape juice cravings was largest in the positive and negative mood conditions. Therefore, although mood did not largely alter neural responses, it did appear to alter subjective craving.