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Chunk #16 — Results — Functional analyses based on miRNA-associated mRNAs in abdominal and gluteal adipose tissue

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MicroRNA expression in abdominal and gluteal adipose tissue is associated with mRNA expression levels and partly genetically driven.
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KEGG terms (see Materials and Methods). The analysis revealed an enrichment of 43 KEGG terms in abdominal adipose tissue (Table S9), and 33 in gluteal adipose tissue (Table S10) (FDR adjusted p-value<0.05). We found that 32 of the KEGG terms were common between the two tissues ( Figure 5B ). Several of these KEGG terms were related to obesity, adipocyte differentiation and metabolic dysregulation; including MAPK signaling pathway, Insulin signaling pathway, Type II diabetes mellitus and Adipocytokine signalling pathway, suggesting relevant functionality.