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Chunk #25 — Unknown Unknowns: Strategies for Exploration — Possible Contribution of Nonadditive Effects

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Knowns and unknowns for psychophysiological endophenotypes: integration and response to commentaries.
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variance (median .05), producing 95% confidence intervals that did not overlap zero (and thus indicated significant dominance effects) for eight of the measures (antisaccade error [7%], skin conductance level [10%], and response frequency [7%], and several EEG measures: occipital-parietal alpha power [5%], beta [4%], theta [10%], delta [13%], and total power [5%]). These results, which were largely nonsignificant or produced small effects, indicate that our molecular-genetic findings were unlikely to be substantially affected by our focus on the additive effects of SNPs.