The fourth aim was addressed by testing if the 76 genes were enriched in pathways/gene sets using Enrichr25,26 and its implemented databases (26 databases). Only pathways enriched with more than two genes were considered. We took a conservative approach and only considered pathways to be significant if the within-database adjusted P-value was smaller than 0.002 (0.05/26 databases evaluated). After correction for the number of databases, no significantly enriched pathways were identified.
