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Chunk #21 — Method — Data Reduction and Analysis

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A multimodal approach to assessing the impact of nicotine dependence, nicotine abstinence, and craving on negative affect in smokers.
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Scoring was conducted offline using AcqKnowledge 3.5.3 software. Data were first visually inspected and edited for movement artifacts and excessive noise. COR EMG was scored in microvolts (μV) after being rectified and integrated using a 20-ms time constant. To minimize the impact of outliers, 1% of observations were trimmed from both sides of the overall distribution for each of the psychophysiological measures (Winer, 1971). The 6 s after the onset of each slide was scored in 1-s epochs for COR EMG. The largest value was selected from among these six epochs to represent the peak response to each slide. We next subtracted the mean of the 2-s baseline prior to the slide onset from these values to get a measure of reactivity to each slide, and then calculated Subject by Session by Slide Valence means of this reactivity score. To obtain a measure of standardized reactivity for each subject, we calculated the standard deviation across all valences, within subject for each session, and divided each reactivity score within session by this standard deviation. This approach produces an effect size statistic,