Table 3 shows the results from the pathway analyses. Where the same gene combination from our input list indicated multiple pathways, we show only the most significant instance to eliminate redundancy. Fourteen pathways were significant at a false discovery rate of 0.01. The 3 most significant pathways were axon guidance (P = 5.26×10−6), developmental biology (P = 1.29×10−5), and neuronal systems (P = 1.37×10−5). Larger pathways, such as these 3 top findings, which each include more than 250 genes, frequently incorporate several more specific themes, and this can be further observed in Table 3. For example, axon guidance includes the smaller L1 cell adhesion molecule (L1CAM) pathway interaction (P = 6.75×10−5), which was also significant in our analysis.
