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Chunk #50 — Materials and Methods — Conditional Analysis

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Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
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The resulting eQTL were further characterized by identifying the list of SNPs associated with each of the peak eSNPs. To this end, all SNPs that are showing significant association with gene expression are assigned to the eSNP with which they have the highest r2. Peaks identified in this way were matched across conditions, and the list of SNPs observed in all treatments in which the peak is present is reported.